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Erectile dysfunction (aka impotence) is an inability to achieve and maintain a proper erection, which results in decrease and absence of sexual activity.

Despite the fact that the vast majority of men suffering from this condition belongs to the elderly age group, it is not associated with a specific age. In fact, erectile dysfunction may be diagnosed at virtually any age.

There is a great numberoffactors leading to this condition, including general stresses, diabetes, heart deceases, metabolic and psychological disorders, smoking, etc.
However, even this condition is not permanent, and its effects can be reversed or compensated following the use of certain drugs, more specifically phosphodiesterase type 5(PDE-5) inhibitors.

This class of drugs used to treat erectile dysfunction includes such brand names as Vardenafil, Viagra,and Cialis (aka Tadalafil).

The Mechanism of Action: A Brief Insight

The mechanism of Cialis’ action involves relaxation of blood vessels and improvement of blood flow to the erectile tissues. From the chemical point of view, its mode of action is rather simple.

In the presence of sexual stimulation, erection is achieved by increasing the cGMP levels in the area of the penis called corpus cavernosum.

The cGMP levels are controlled by another group of enzymes preventing their concentration. The active ingredients of the drug block the operation of the cGMP-specific phosphodiesterase type 5 (PDE5) enzymes.

This helps to relax (widen) blood vessels and improves the flow of blood to the tissues of penis following sexual stimulation. This helps both get and maintain an erection. Thus the concentrated quantities of cGMP become enough to maintain aproper erection.

What are the Expected Side Effects?

This article contains a concise register of the most common side effects of Cialis (Tadalafil) that may be potentially experienced by some patients.

The best place to find a full list of the side effects that can be associated with your medicine is from the manufacturer's printed information leaflet supplied with the medicine.

Alternatively, you can find an example of a manufacturer’s information leaflet in the reference section below.

The side effects of using Cialis have been documented sufficiently and are already mentioned in the drug’s instructions. These adverse reactions often vary in both rarity and severity. Some of them are not even alarming since they are usually just forms of theinitial reaction of the body towards the drug.

Some of the most common side effects include flushing, sneezing, nasal congestion, insomnia, pains or ache in the muscles. Immediately contact your doctor or pharmacist if any of the following continue or become troublesome.

There are also others that are rare but also belong in the same non-alarming category. Such are mild ear pain, periods of anxiety, difficulty in swallowing, cough, nausea, fatigue. However, these symptoms usually disappear for a short while. If any of these symptoms persist, it is better to consult a physician.

The more serious side effects are extremely rare but it is an obligation of every company towards its customers to include them too.

Some of them are blurred vision, indigestion, higher than usual urination frequency, bladder pain and blood in urine, digestion difficulties, dizziness, chest pains, dry mouth, increased heart rate, double vision, abnormal sweating, sudden changes in blood pressure, skin rashes, increased skin sensitivity, inability to tolerate bright light.

All of the above are matters that require immediate medical attention.

Before Taking Cialis

A list of conditions and chronic diseases that make it dangerous and/or unacceptable to take the drug includes rather a moderate number of issues, though it makes it even more important to follow its recommendations.

For these reasons, before you start using Cialis (Tadalafil) it is important that your pharmacist knows:

• If you have any disease, injury or congenital or acquireddeformity of the penis.
• If you have a heart condition or any kind of blood vessel disease.
• If you have had a heart attack.
• If you have low blood pressure or angina.
• If you have had an eye condition causing temporary loss of vision.
• If you have sickle cell disease.
• If you have any type of liver and/or kidney disease.
• If you have ever had bone marrow cancer or leukemia.
• If you are taking or using any other drugs, including any drugs thatare available without a prescription, as well as herbal and complementary medicinesor recreational drugs.
• If you have ever had an allergic reaction to any ingredient of the drug.

Consultation with a doctor is critically necessary in case if you experience any other symptoms which you think may be due to the tablets.

Important: if you get an erection, which lasts for longer than four hours, or if you get chest pains or a sudden loss of vision, contact a doctor for medical attention straightaway.

Other Indications for Use

Cialis is also prescribed for men with prostate gland enlargement. The prostate gland commonly becomes larger in older men. The condition is also called benign prostatic hyperplasia (BPH).

The prostate is situated close to the bladder, so its enlargement can cause problems with passing urine. Cialis works by improving the blood flow to the prostate and bladder, and by relaxing the muscles in these areas. These actions help urine to follow more easily.